FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term Dom34-Hbs1 complex ID (Ontology) GO:1990533 (Gene Ontology)
Definition A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay.[ PubMed:20890290 PubMed:21102444 PubMed:21448132 PubMed:22503425 ]
Also Known As "Dom34:Hbs1 complex"
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       1
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 Dom34-Hbs1 complex (all annotations which use CV term, excluding "NOT" statements)       1
     part_of | Dom34-Hbs1 complex       1
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       |__Dom34-Hbs1 complex  1 rec.
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