FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term I(KACh) inward rectifier potassium channel complex ID (Ontology) GO:1990566 (Gene Ontology)
Definition An inward rectifier potassium channel complex expressed in cardiac muscle, specifically the sinoatrial node and atria, where it controls the heart rate, via regulation by G protein-coupled receptor signaling. In mammals it is composed of GIRK1 (or Kir3.1) and GIRK4 (or Kir3.4) subunits.[ PubMed:9765280 ]
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  voltage-gated potassium channel complex
   |__inward rectifier potassium channel complex
       |__I(KACh) inward rectifier potassium channel complex
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Synonyms
  • "GIRK1-GIRK4 G protein-coupled atrial inward rectifier potassium channel complex" RELATED
    "Kir3.1-Kir3.4 G protein-coupled atrial inward rectifier potassium channel complex" RELATED
    "muscarinic potassium channel complex" RELATED
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