FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term ATF4-CREB1 transcription factor complex ID (Ontology) GO:1990589 (Gene Ontology)
Definition Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway.[ PubMed:12871976 ]
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transcription regulator complex_____
nuclear protein-containing complex__|
                                    RNA polymerase II transcription regulator complex
                                     |__ATF4-CREB1 transcription factor complex
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Is a RNA polymerase II transcription regulator complex
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