FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term phospholamban complex ID (Ontology) GO:1990629 (Gene Ontology)
Definition A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac PLN is a main determinant of muscle contraction and relaxation, by regulating intracellular calcium levels.[ PubMed:16043693 ]
Also Known As "cardiac phospholamban complex"
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endoplasmic reticulum
 |__endoplasmic reticulum protein-containing complex__
endoplasmic reticulum membrane                        |
 |__sarcoplasmic reticulum membrane___________________|
membrane                                              |
 |__membrane protein complex__________________________|
sarcoplasmic reticulum                                |
 |__sarcoplasmic reticulum membrane___________________|
protein-containing complex                            |
 |__membrane protein complex__________________________|
 |__endoplasmic reticulum protein-containing complex__|
bounding membrane of organelle                        |
 |__sarcoplasmic reticulum membrane___________________|
                                                      phospholamban complex
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Is a membrane protein complex
endoplasmic reticulum protein-containing complex
Part of sarcoplasmic reticulum membrane
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Synonyms
  • "cardiac phospholamban complex" EXACT
    "cardiac PLB complex" RELATED
    "cardiac PLN complex" RELATED
Secondary IDs
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