Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Term | mutator focus | ID (Ontology) | GO:1990633 (Gene Ontology) |
| Definition | A type of punctate focus localized to the perinuclear region of germline cytoplasm in C. elegans. Mutator foci are required for RNA interference (RNAi) and serve as sites of small inhibitory RNA (siRNA) amplification. As such, proteins that localize to mutator foci include RNA-directed RNA polymerases (RdRPs) and beta-nucleotidyltransferases. Mutator foci are distinct from, but adjacent to or partially overlap, P granules.[ PubMed:22713602 PubMed:25635455 ] | ||
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cytoplasm |__cytoplasmic ribonucleoprotein granule__ |__perinuclear region of cytoplasm________| ribonucleoprotein granule | |__cytoplasmic ribonucleoprotein granule__| cellular anatomical structure | |__perinuclear region of cytoplasm________| mutator focus |
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| Is a | cytoplasmic ribonucleoprotein granule | ||
| Part of | perinuclear region of cytoplasm | ||
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