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| Term | PCSK9-LDLR complex | ID (Ontology) | GO:1990666 (Gene Ontology) |
| Definition | A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and a low-density lipoprotein receptor (LDLR). Interaction typically occurs through the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR, and complex formation promotes degradation of the LDLR through the endosome/lysosome pathway.[ PubMed:18250299 PubMed:24440079 ] | ||
| Also Known As | "PCSK9.LDLR complex" ; "PCSK9/LDL-R complex" ; "PCSK9:low-density lipoprotein receptor complex" | ||
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cellular_component |__protein-containing complex |__PCSK9-LDLR complex |
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| Is a | protein-containing complex | ||
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