FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term titin-telethonin complex ID (Ontology) GO:1990733 (Gene Ontology)
Definition A protein complex formed between the N-terminus of the giant sarcomeric filament protein titin and the Z-disk ligand, telethonin. The complex is part of the Z-disk of the skeletal and cardiac sarcomere. Telethonin binding to titin might be essential for the initial assembly, stabilization and functional integrity of the titin filament, and hence important for muscle contraction relaxation in mature myofibrils.[ PubMed:16407954 ]
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  cellular_component
   |__protein-containing complex
       |__titin-telethonin complex
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Is a protein-containing complex
Part of Z disc
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Synonyms
  • "Titin-Tcap complex" RELATED
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