| General Information | |||
|---|---|---|---|
| Term | NPHP complex | ID (Ontology) | GO:1990957 (Gene Ontology) |
| Definition | A protein complex that is located at the ciliary transition zone and consists of the NPHP4 and NPHP1 proteins. It acts as an organiser of the transition zone inner structure, specifically the Y-shaped links, in conjunction with the MKS complex. It is involved in ciliary protein trafficking and is required for correct functioning of the WNT and Hippo signaling pathways.[ PubMed:18337471 PubMed:21422230 PubMed:21498478 PubMed:21555462 PubMed:25150219 ] | ||
| Also Known As | "NPHP module" | ||
| Comment | |||
| Links to External Ontologies | |||
| QuickGO data AmiGO data | |||
| Annotations | |||
| Records annotated with this term OR any of its CHILD TERMS | |||
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
|
|||
|
No relevant statements available
|
|||
cellular_component |__protein-containing complex__ cilium | |__ciliary transition zone_____| cellular anatomical structure | |__ciliary transition zone_____| NPHP complex |
| Spanning Tree View Settings | |||
|---|---|---|---|
| Parents/Children View Depth |
|||
Relationships
|
|||
| Is a | protein-containing complex | ||
| Part of | ciliary transition zone | ||
Synonyms & Secondary IDs
|
|||
| Synonyms | |||
|
|||
| Secondary IDs | |||
|
|
|||
External Crossreferences & Linkouts
|
|||