FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term U2_snRNA ID (Ontology) SO:0000392 (Sequence Ontology)
Definition U2 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Complementary binding between U2 snRNA (in an area lying towards the 5' end but 3' to hairpin I) and the branchpoint sequence (BPS) of the intron results in the bulging out of an unpaired adenine, on the BPS, which initiates a nucleophilic attack at the intronic 5' splice site, thus starting the first of two transesterification reactions that mediate splicing.
Also Known As "small nuclear RNA U2" ; "snRNA U2" ; "U2 small nuclear RNA" (for all, see Synonyms field below)
Comment
Links to External Ontologies
SO.org
Annotations
Records annotated with this term OR any of its CHILD TERMS
No relevant records available
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available
Spanning Tree (Parents/Children)
Only view relationship: 
  sncRNA
   |__snRNA
       |__U2_snRNA
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a snRNA
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "small nuclear RNA U2" EXACT
    "snRNA U2" EXACT
    "U2 small nuclear RNA" EXACT
    "U2 snRNA" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
http://en.wikipedia.org/wiki/U2_snRNA "wiki"