FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term glioblastoma ID (Ontology) DOID:3068 (Human Disease)
Definition A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
Also Known As "adult glioblastoma multiforme" ; "GBM" ; "glioblastoma multiforme" (for all, see Synonyms field below)
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DO.org
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Data Class Field Records
Alleles (FBal)  HUMAN_DISEASE_INTERACTIONS      16
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 Alleles Genes
 glioblastoma      16     11
 ameliorates | glioblastoma      13       --
 model of | glioblastoma       3       --
Spanning Tree (Parents/Children)
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high grade glioma______________
central nervous system cancer__|
                               malignant astrocytoma
                                |__glioblastoma  27 rec.
                                    |__giant cell glioblastoma
                                    |__glioblastoma classical subtype
                                    |__glioblastoma mesenchymal subtype
                                    |__glioblastoma neural subtype
                                    |__glioblastoma proneural subtype
                                    |__gliosarcoma
                                    |__IDH-wildtype glioblastoma
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Is a malignant astrocytoma
Part of
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Synonyms
  • "adult glioblastoma multiforme" EXACT
    "GBM" EXACT OMO:0003012
    "glioblastoma multiforme" EXACT
    "grade IV adult Astrocytic tumor" EXACT
    "primary glioblastoma multiforme" EXACT
    "spongioblastoma multiforme" EXACT
Secondary IDs
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GARD:2491
ICDO:9440/3
MESH:D005909
NCI:C129295
NCI:C39750
NCI:C9094
SNOMEDCT_US_2023_03_01:63634009
UMLS_CUI:C0017636
UMLS_CUI:C0278878
UMLS_CUI:C1514422