FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term double-strand break repair via homologous recombination ID (Ontology) GO:0000724 (Gene Ontology)
Definition The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.[ PubMed:10357855 ]
Also Known As "HDR" ; "homologous recombinational repair" ; "homology-directed repair" (for all, see Synonyms field below)
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      43
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 double-strand break repair via homologous recombination (all annotations which use CV term, excluding "NOT" statements)      43
     involved_in | double-strand break repair via homologous recombination      43
Spanning Tree (Parents/Children)
Only view relationship: 
DNA repair
 |__recombinational repair______
 |__double-strand break repair__|
DNA recombination               |
 |__recombinational repair______|
                                double-strand break repair via homologous recombination  66 rec.
                                 |__double-strand break repair via break-induced replication 13 rec.
                                 |__double-strand break repair via synthesis-dependent strand annealing 11 rec.
                                 |__double-strand break repair via transcription-associated homologous recombination
                                 |__replication-born double-strand break repair via sister chromatid exchange 2 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a recombinational repair
double-strand break repair
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "HDR" EXACT
    "homologous recombinational repair" EXACT
    "homology-directed repair" EXACT
    "HRR" EXACT
    "Rad51-dependent recombinational repair" EXACT
    "Rhp51-dependent recombinational repair" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-5693538 "Homology Directed Repair"