FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term negative regulation of cytokine production ID (Ontology) GO:0001818 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the rate of production of a cytokine.[ ISBN:0781735149 ]
Also Known As "down regulation of cytokine biosynthetic process" ; "down regulation of cytokine production" ; "down-regulation of cytokine biosynthetic process" (for all, see Synonyms field below)
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
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 negative regulation of cytokine production (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | negative regulation of cytokine production       1
Spanning Tree (Parents/Children)
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regulation of gene expression
 |__regulation of cytokine production________________________
 |__negative regulation of gene expression___________________|
negative regulation of macromolecule biosynthetic process    |
 |__negative regulation of gene expression___________________|
negative regulation of biological process                    |
 |__negative regulation of multicellular organismal process__|
regulation of multicellular organismal process               |
 |__regulation of cytokine production________________________|
 |__negative regulation of multicellular organismal process__|
                                                             negative regulation of cytokine production  2 rec.
                                                              |__negative regulation of chemokine production
                                                              |   |__negative regulation of chemokine (C-C motif) ligand 1 production
                                                              |   |__negative regulation of chemokine (C-C motif) ligand 4 production
                                                              |   |__negative regulation of chemokine (C-C motif) ligand 5 production
                                                              |   |__negative regulation of chemokine (C-C motif) ligand 6 production
                                                              |   |__negative regulation of chemokine (C-C motif) ligand 20 production
                                                              |   |__negative regulation of chemokine (C-X-C motif) ligand 1 production
                                                              |   |__negative regulation of chemokine (C-X-C motif) ligand 2 production
                                                              |   |__negative regulation of chemokine (C-X-C motif) ligand 9 production
                                                              |   |__negative regulation of fractalkine production
                                                              |   |__negative regulation of IP-10 production
                                                              |   |__negative regulation of macrophage inflammatory protein 1 alpha production
                                                              |   |__negative regulation of macrophage inflammatory protein-1 gamma production
                                                              |   |__negative regulation of monocyte chemotactic protein-1 production
                                                              |__negative regulation of connective tissue growth factor production
                                                              |__negative regulation of cytokine production involved in immune response 1 rec.
                                                              |   |__negative regulation of B cell cytokine production
                                                              |   |__negative regulation of dendritic cell cytokine production(+)
                                                              |   |__negative regulation of macrophage cytokine production 1 rec.
                                                              |   |__negative regulation of mast cell cytokine production
                                                              |   |__negative regulation of natural killer cell cytokine production
                                                              |   |__negative regulation of T cell cytokine production(+)
                                                              |__negative regulation of cytokine production involved in inflammatory response
                                                              |__negative regulation of endothelin production
                                                              |__negative regulation of fibroblast growth factor production
                                                              |__negative regulation of glial cell-derived neurotrophic factor production
                                                              |__negative regulation of granulocyte macrophage colony-stimulating factor production
                                                              |__negative regulation of hepatocyte growth factor production
                                                              |__negative regulation of interleukin-1 production
                                                              |   |__negative regulation of interleukin-1 alpha production
                                                              |   |__negative regulation of interleukin-1 beta production
                                                              |__negative regulation of interleukin-2 production
                                                              |__negative regulation of interleukin-3 production
                                                              |__negative regulation of interleukin-4 production
                                                              |__negative regulation of interleukin-5 production
                                                              |__negative regulation of interleukin-6 production
                                                              |__negative regulation of interleukin-7 production
                                                              |__negative regulation of interleukin-8 production
                                                              |__negative regulation of interleukin-9 production
                                                              |__negative regulation of interleukin-10 production
                                                              |__negative regulation of interleukin-11 production
                                                              |__negative regulation of interleukin-12 production
                                                              |__negative regulation of interleukin-13 production
                                                              |__negative regulation of interleukin-15 production
                                                              |__negative regulation of interleukin-16 production
                                                              |__negative regulation of interleukin-17 production
                                                              |   |__negative regulation of interleukin-17A production
                                                              |__negative regulation of interleukin-18 production
                                                              |__negative regulation of interleukin-19 production
                                                              |__negative regulation of interleukin-20 production
                                                              |__negative regulation of interleukin-21 production
                                                              |__negative regulation of interleukin-22 production
                                                              |__negative regulation of interleukin-23 production
                                                              |__negative regulation of interleukin-24 production
                                                              |__negative regulation of interleukin-25 production
                                                              |__negative regulation of interleukin-26 production
                                                              |__negative regulation of interleukin-27 production
                                                              |__negative regulation of interleukin-32 production
                                                              |__negative regulation of interleukin-33 production
                                                              |__negative regulation of interleukin-34 production
                                                              |__negative regulation of interleukin-35 production
                                                              |__negative regulation of interleukin-37 production
                                                              |__negative regulation of macrophage colony-stimulating factor production
                                                              |   |__negative regulation of granulocyte colony-stimulating factor production
                                                              |__negative regulation of transforming growth factor beta production
                                                              |   |__negative regulation of transforming growth factor beta1 production
                                                              |   |__negative regulation of transforming growth factor beta2 production
                                                              |   |__negative regulation of transforming growth factor beta3 production
                                                              |__negative regulation of tumor necrosis factor superfamily cytokine production
                                                              |   |__negative regulation of lymphotoxin A production
                                                              |   |__negative regulation of TRAIL production
                                                              |   |__negative regulation of tumor necrosis factor (ligand) superfamily member 11 production
                                                              |   |__negative regulation of tumor necrosis factor production
                                                              |__negative regulation of type I interferon production
                                                              |   |__negative regulation of interferon-alpha production
                                                              |   |__negative regulation of interferon-beta production
                                                              |__negative regulation of type II interferon production
                                                              |__negative regulation of type III interferon production
                                                              |__negative regulation of vascular endothelial growth factor production
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Is a regulation of cytokine production
negative regulation of gene expression
negative regulation of multicellular organismal process
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Synonyms
  • "down regulation of cytokine biosynthetic process" EXACT
    "down regulation of cytokine production" EXACT
    "down-regulation of cytokine biosynthetic process" EXACT
    "down-regulation of cytokine production" EXACT
    "downregulation of cytokine biosynthetic process" EXACT
    "downregulation of cytokine production" EXACT
    "inhibition of cytokine biosynthetic process" NARROW
    "inhibition of cytokine production" NARROW
    "negative regulation of cytokine anabolism" EXACT
    "negative regulation of cytokine biosynthesis" EXACT
    "negative regulation of cytokine biosynthetic process" NARROW
    "negative regulation of cytokine formation" EXACT
    "negative regulation of cytokine secretion" NARROW
    "negative regulation of cytokine synthesis" EXACT
Secondary IDs
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