FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term transcription factor TFIIH holo complex ID (Ontology) GO:0005675 (Gene Ontology)
Definition A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of the core TFIIH complex and the TFIIK complex.[ PubMed:14500720 PubMed:22308316 PubMed:22572993 PubMed:7813015 ]
Also Known As "cyclin-dependent protein kinase activating kinase holoenzyme complex" ; "holo TFIIH complex"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT      10
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Relevant FlyBase reports
 Gene Groups Genes
 transcription factor TFIIH holo complex (all annotations which use CV term, excluding "NOT" statements)       2     10
     part_of | transcription factor TFIIH holo complex       --      10
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cyclin-dependent protein kinase holoenzyme complex
 |__nuclear cyclin-dependent protein kinase holoenzyme complex__
transcription regulator complex                                 |
 |__RNA polymerase II transcription regulator complex___________|
nuclear protein-containing complex                              |
 |__nuclear cyclin-dependent protein kinase holoenzyme complex__|
 |__carboxy-terminal domain protein kinase complex______________|
 |__RNA polymerase II transcription regulator complex___________|
serine/threonine protein kinase complex                         |
 |__carboxy-terminal domain protein kinase complex______________|
                                                                transcription factor TFIIH holo complex  13 rec.
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Is a nuclear cyclin-dependent protein kinase holoenzyme complex
carboxy-terminal domain protein kinase complex
RNA polymerase II transcription regulator complex
Part of RNA polymerase II, holoenzyme
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Synonyms
  • "CAK complex" RELATED
    "CDK-activating kinase" BROAD
    "cyclin-dependent protein kinase activating kinase holoenzyme complex" EXACT
    "holo TFIIH complex" EXACT
Secondary IDs
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