FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term late endosome ID (Ontology) GO:0005770 (Gene Ontology)
Definition A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.[ PubMed:11964142 PubMed:2557062 ]
Also Known As "prevacuolar compartment"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      22
Genes (FBgn)  GO_CELLULAR_COMPONENT      55
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      12
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Constructs
 late endosome (all annotations which use CV term, excluding "NOT" statements)      23     57     12
     colocalizes_with | late endosome       --       6       --
     is_active_in | late endosome       --      11       --
     late endosome | adult stage       4       --       2
     late endosome | adult stage | increased number       3       --       3
     late endosome | cell autonomous | somatic clone | third instar larval stage       4       --       3
     late endosome | germline clone | oogenesis       1       --       --
     late endosome | increased number       3       --       1
     late endosome | larval stage      19       --      10
     late endosome | somatic clone       3       --       1
     late endosome | third instar larval stage      12       --       2
     located_in | late endosome       --      43       --
Spanning Tree (Parents/Children)
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  cytoplasmic vesicle
   |__endosome
       |__late endosome  168 rec.
           |__multivesicular body 58 rec.
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Synonyms
  • "prevacuolar compartment" EXACT
    "PVC" BROAD
Secondary IDs
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NIF_Subcellular:nlx_subcell_20090702