FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term bicellular tight junction ID (Ontology) GO:0005923 (Gene Ontology)
Definition An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.[ ISBN:0815332181 ]
Also Known As "zonula occludens"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       2
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Relevant FlyBase reports
 Alleles Genes
 bicellular tight junction (all annotations which use CV term, excluding "NOT" statements)       --       2
     bicellular tight junction | embryonic stage       1       --
     is_active_in | bicellular tight junction       --       1
     located_in | bicellular tight junction       --       1
Spanning Tree (Parents/Children)
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  cell-cell junction
   |__tight junction
       |__bicellular tight junction  2 rec.
           |__host-symbiont bicellular tight junction
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Is a tight junction
Part of apical junction complex
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Synonyms
  • "zonula occludens" EXACT
Secondary IDs
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NIF_Subcellular:sao1939999134
Wikipedia:Tight_junction