FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term nucleotide-excision repair ID (Ontology) GO:0006289 (Gene Ontology)
Definition A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).[ PubMed:10197977 ]
Also Known As "NER" ; "pyrimidine-dimer repair, DNA damage excision"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      23
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 nucleotide-excision repair (all annotations which use CV term, excluding "NOT" statements)      23
     involved_in | nucleotide-excision repair      23
Spanning Tree (Parents/Children)
Only view relationship: 
DNA metabolic process__
DNA damage response____|
                       DNA repair
                        |__nucleotide-excision repair  28 rec.
                            |__global genome nucleotide-excision repair
                            |__nucleotide-excision repair involved in interstrand cross-link repair 3 rec.
                            |__pyrimidine dimer repair by nucleotide-excision repair
                            |__transcription-coupled nucleotide-excision repair 1 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a DNA repair
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "intrastrand cross-link repair" RELATED
    "NER" EXACT
    "pyrimidine-dimer repair, DNA damage excision" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-5696398 "Nucleotide Excision Repair"
Reactome:R-HSA-5696400 "Dual Incision in GG-NER"