General Information
Term	complement activation	ID (Ontology)	GO:0006956 (Gene Ontology)
Definition	Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.[ ISBN:0781735149 ]
Also Known As	"complement cascade" ; "complement response"
Comment
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	QuickGO data AmiGO data
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available

General Information

Term

complement activation

ID (Ontology)

GO:0006956 (Gene Ontology)

Definition

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.[ ISBN:0781735149 ]

Also Known As

"complement cascade" ; "complement response"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

immune system process
 |__immune effector process_____________
 |__activation of immune response_______|
immune response                         |
 |__humoral immune response_____________|
positive regulation of immune response  |
 |__activation of immune response_______|
                                        complement activation
                                         |__activation of membrane attack complex
                                         |__complement activation, alternative pathway
                                         |__complement activation, classical pathway
                                         |__complement activation, GZMK pathway
                                         |__complement activation, lectin pathway

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Is a	immune effector process activation of immune response humoral immune response
Part of
Synonyms & Secondary IDs
Synonyms
	"complement activity" RELATED "complement cascade" EXACT "complement response" EXACT
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-166658 "Complement cascade"

Spanning Tree View Settings

Parents/Children
View Depth

Relationships

Is a

immune effector process
activation of immune response
humoral immune response

Part of

Synonyms & Secondary IDs

Synonyms

"complement activity" RELATED
"complement cascade" EXACT
"complement response" EXACT

Secondary IDs

External Crossreferences & Linkouts

Reactome:R-HSA-166658 "Complement cascade"