FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term RNA polymerase II, holoenzyme ID (Ontology) GO:0016591 (Gene Ontology)
Definition A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters.[ PubMed:16858867 ]
Also Known As "DNA-directed RNA polymerase II, holoenzyme"
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DNA-directed RNA polymerase complex__
nuclear protein-containing complex___|
                                     nuclear DNA-directed RNA polymerase complex
                                      |__RNA polymerase II, holoenzyme  83 rec.
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