FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term plasma membrane phospholipid scrambling ID (Ontology) GO:0017121 (Gene Ontology)
Definition The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE).[ PubMed:20043909 PubMed:20302864 ]
Also Known As "PL scrambling"
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       6
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Relevant FlyBase reports
 Gene Groups Genes
 plasma membrane phospholipid scrambling (all annotations which use CV term, excluding "NOT" statements)       1      6
     involved_in | plasma membrane phospholipid scrambling       --       6
Spanning Tree (Parents/Children)
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phospholipid transport
 |__phospholipid translocation____
lipid translocation               |
 |__phospholipid translocation____|
membrane organization             |
 |__plasma membrane organization__|
                                  plasma membrane phospholipid scrambling  8 rec.
                                   |__calcium activated phospholipid scrambling
                                   |   |__calcium activated galactosylceramide scrambling
                                   |   |__calcium activated phosphatidylcholine scrambling
                                   |   |__calcium activated phosphatidylserine scrambling
                                   |__phosphatidylserine exposure on apoptotic cell surface 2 rec.
                                   |__phosphatidylserine exposure on blood platelet
                                   |__phosphatidylserine exposure on osteoblast involved in bone mineralization
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Is a plasma membrane organization
phospholipid translocation
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Synonyms
  • "phospholipid scrambling" RELATED
    "PL scrambling" EXACT
Secondary IDs
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