FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term secretory granule ID (Ontology) GO:0030141 (Gene Ontology)
Definition A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.[ ISBN:0198506732 ]
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      20
Genes (FBgn)  GO_CELLULAR_COMPONENT      10
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      12
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Constructs
 secretory granule (all annotations which use CV term, excluding "NOT" statements)      20     10     12
     colocalizes_with | secretory granule       --       1       --
     is_active_in | secretory granule       --       5       --
     located_in | secretory granule       --       5       --
     secretory granule | ectopic | prepupal stage       1       --       --
     secretory granule | larval stage       8       --       6
     secretory granule | third instar larval stage       2       --       --
Spanning Tree (Parents/Children)
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  cytoplasmic vesicle
   |__secretory vesicle
       |__secretory granule  63 rec.
           |__acrosomal vesicle 6 rec.
           |__apicomplexan dense granule
           |__azurophil granule
           |__chromaffin granule
           |__cortical granule
           |__dense core granule 6 rec.
           |   |__neuronal dense core vesicle
           |__ficolin-1-rich granule
           |__insulin-responsive compartment
           |__lamellar body 4 rec.
           |   |__alveolar lamellar body
           |   |__dendritic lamellar body
           |   |__epidermal lamellar body
           |__mucin granule
           |__mucocyst
           |__platelet alpha granule
           |__platelet dense granule
           |__specific granule
           |__tertiary granule
           |__Weibel-Palade body
           |__zymogen granule
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Is a secretory vesicle
Part of endomembrane system
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Synonyms
  • "secretory vesicle" BROAD
Secondary IDs
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