FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term protein catabolic process ID (Ontology) GO:0030163 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
Also Known As "cellular protein breakdown" ; "cellular protein catabolic process" ; "cellular protein catabolism" (for all, see Synonyms field below)
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      12
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 protein catabolic process (all annotations which use CV term, excluding "NOT" statements)      12
     involved_in | protein catabolic process      12
Spanning Tree (Parents/Children)
Only view relationship:
catabolic process
 |__macromolecule catabolic process__
macromolecule metabolic process      |
 |__macromolecule catabolic process__|
 |__protein metabolic process________|
primary metabolic process            |
 |__protein metabolic process________|
                                     protein catabolic process  443 rec.
                                      |__chaperone-mediated autophagy
                                      |__epidermal growth factor catabolic process
                                      |__glycoprotein catabolic process 18 rec.
                                      |   |__elastin catabolic process
                                      |   |__O-sialoglycoprotein catabolic process
                                      |   |__proteoglycan catabolic process(+) 11 rec.
                                      |   |__ubiquitin-dependent glycoprotein ERAD pathway 3 rec.
                                      |__hemoglobin catabolic process
                                      |__histone catabolic process
                                      |__insulin catabolic process 1 rec.
                                      |__lipoprotein catabolic process 1 rec.
                                      |   |__protein depalmitoleylation 1 rec.
                                      |   |__protein depalmitoylation
                                      |__low-density lipoprotein particle receptor catabolic process
                                      |__mitochondrial protein catabolic process 3 rec.
                                      |__proteasomal protein catabolic process 314 rec.
                                      |   |__EGAD pathway
                                      |   |__ERAD pathway(+) 46 rec.
                                      |   |__proteasomal ubiquitin-independent protein catabolic process 1 rec.
                                      |   |__proteasome-mediated ubiquitin-dependent protein catabolic process(+) 270 rec.
                                      |__protein catabolic process at synapse
                                      |   |__protein catabolic process at postsynapse
                                      |   |__protein catabolic process at presynapse
                                      |   |__protein catabolic process, modulating synaptic transmission
                                      |__protein catabolic process in the vacuole 3 rec.
                                      |   |__lysosomal protein catabolic process 3 rec.
                                      |__protein denaturation
                                      |__PSII associated light-harvesting complex II catabolic process
                                      |__rhodopsin catabolic process
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Is a macromolecule catabolic process
protein metabolic process
Part of
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Synonyms
  • "cellular protein breakdown" EXACT
    "cellular protein catabolic process" EXACT
    "cellular protein catabolism" EXACT
    "cellular protein degradation" EXACT
    "multicellular organismal protein catabolic process" NARROW
    "pheromone catabolic process" RELATED
    "pheromone catabolism" RELATED
    "protein breakdown" EXACT
    "protein catabolism" EXACT
    "protein degradation" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Wikipedia:Protein_catabolism