FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term V(D)J recombination ID (Ontology) GO:0033151 (Gene Ontology)
Definition The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).[ ISBN:0781700221 ISBN:0781735149 ]
Also Known As "V(D)J joining" ; "V-D-J joining" ; "V-D-J recombination" (for all, see Synonyms field below)
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somatic diversification of immune receptors__
somatic cell DNA recombination_______________|
                                             somatic diversification of immune receptors via germline recombination within a single locus
                                              |__V(D)J recombination
                                                  |__immunoglobulin V(D)J recombination
                                                  |   |__immunoglobulin heavy chain V-D-J recombination
                                                  |   |__immunoglobulin light chain V-J recombination
                                                  |__T cell receptor V(D)J recombination
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Is a somatic diversification of immune receptors via germline recombination within a single locus
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Synonyms
  • "V(D)J joining" EXACT
    "V-D-J joining" EXACT
    "V-D-J recombination" EXACT
    "V-J joining" EXACT
    "V-J recombination" EXACT
Secondary IDs
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Wikipedia:V(D)J_recombination