FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term TIRAP-dependent toll-like receptor signaling pathway ID (Ontology) GO:0035664 (Gene Ontology)
Definition The series of molecular signals initiated by a ligand binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.[ PubMed:11526399 PubMed:11544529 PubMed:12447442 ]
Also Known As "MAL-dependent toll-like receptor signaling pathway" ; "MyD88 adapter-like dependent toll-like receptor signaling pathway" ; "TIRAP-dependent TLR signaling pathway" (for all, see Synonyms field below)
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  pattern recognition receptor signaling pathway
   |__toll-like receptor signaling pathway
       |__TIRAP-dependent toll-like receptor signaling pathway
           |__TIRAP-dependent toll-like receptor 4 signaling pathway
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Is a toll-like receptor signaling pathway
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Synonyms
  • "MAL-dependent toll-like receptor signaling pathway" EXACT[ PubMed:11544529 ]
    "MyD88 adapter-like dependent toll-like receptor signaling pathway" EXACT[ PubMed:11544529 ]
    "TIRAP-dependent TLR signaling pathway" EXACT
    "TIRAP-dependent toll-like receptor signalling pathway" EXACT
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