General Information
Term	negative regulation of signal transduction by receptor internalization	ID (Ontology)	GO:0038011 (Gene Ontology)
Definition	Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands.[ PubMed:17908284 PubMed:19696798 ]
Also Known As	"negative regulation of signaling pathway by receptor endocytosis"
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General Information

Term

negative regulation of signal transduction by receptor internalization

ID (Ontology)

GO:0038011 (Gene Ontology)

Definition

Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands.[ PubMed:17908284 PubMed:19696798 ]

Also Known As

"negative regulation of signaling pathway by receptor endocytosis"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

regulation of signal transduction
 |__negative regulation of signal transduction_____________________
 |__regulation of signal transduction by receptor internalization__|
negative regulation of cell communication                          |
 |__negative regulation of signal transduction_____________________|
negative regulation of signaling                                   |
 |__negative regulation of signal transduction_____________________|
receptor internalization                                           |
 |__regulation of signal transduction by receptor internalization__|
negative regulation of response to stimulus                        |
 |__negative regulation of signal transduction_____________________|
                                                                   negative regulation of signal transduction by receptor internalization
                                                                    |__negative regulation of insulin receptor signaling pathway by insulin receptor internalization

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Synonyms
	"negative regulation of signaling pathway by receptor endocytosis" EXACT
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negative regulation of signal transduction
regulation of signal transduction by receptor internalization

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Synonyms & Secondary IDs

Synonyms

"negative regulation of signaling pathway by receptor endocytosis" EXACT

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