FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term positive regulation of apoptotic process ID (Ontology) GO:0043065 (Gene Ontology)
Definition Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
Also Known As "up regulation of apoptosis" ; "up-regulation of apoptosis" ; "upregulation of apoptosis"
Comment
Links to External Ontologies
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      42
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 positive regulation of apoptotic process (all annotations which use CV term, excluding "NOT" statements)       1     42
     acts_upstream_of | positive regulation of apoptotic process       --       7
     involved_in | positive regulation of apoptotic process       --      35
Spanning Tree (Parents/Children)
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regulation of programmed cell death
 |__regulation of apoptotic process_______________
 |__positive regulation of programmed cell death__|
positive regulation of cellular process           |
 |__positive regulation of programmed cell death__|
                                                  positive regulation of apoptotic process  67 rec.
                                                   |__positive regulation of anoikis
                                                   |__positive regulation of apoptotic process in bone marrow cell
                                                   |__positive regulation of apoptotic process involved in development 9 rec.
                                                   |   |__positive regulation of apoptotic process involved in metanephric collecting duct development
                                                   |   |__positive regulation of apoptotic process involved in metanephric nephron tubule development
                                                   |   |__positive regulation of apoptotic process involved in morphogenesis(+) 2 rec.
                                                   |   |__positive regulation of B cell deletion(+)
                                                   |   |__positive regulation of mesenchymal cell apoptotic process involved in metanephros development(+)
                                                   |   |__positive regulation of nurse cell apoptotic process 5 rec.
                                                   |__positive regulation of apoptotic signaling pathway 6 rec.
                                                   |   |__positive regulation of extrinsic apoptotic signaling pathway(+)
                                                   |   |__positive regulation of intrinsic apoptotic signaling pathway(+) 3 rec.
                                                   |__positive regulation of compound eye retinal cell apoptotic process 1 rec.
                                                   |__positive regulation of endothelial cell apoptotic process
                                                   |__positive regulation of epithelial cell apoptotic process
                                                   |   |__positive regulation of cholangiocyte apoptotic process
                                                   |   |__positive regulation of granulosa cell apoptotic process
                                                   |   |__positive regulation of hepatocyte apoptotic process
                                                   |   |__positive regulation of keratinocyte apoptotic process
                                                   |   |__positive regulation of podocyte apoptotic process
                                                   |   |__positive regulation of type B pancreatic cell apoptotic process
                                                   |__positive regulation of execution phase of apoptosis
                                                   |__positive regulation of fat cell apoptotic process
                                                   |__positive regulation of fibroblast apoptotic process
                                                   |__positive regulation of glial cell apoptotic process 1 rec.
                                                   |   |__positive regulation of oligodendrocyte apoptotic process
                                                   |__positive regulation of leukocyte apoptotic process
                                                   |   |__positive regulation of dendritic cell apoptotic process
                                                   |   |__positive regulation of lymphocyte apoptotic process(+)
                                                   |   |__positive regulation of macrophage apoptotic process
                                                   |   |__positive regulation of mast cell apoptotic process
                                                   |   |__positive regulation of neutrophil apoptotic process
                                                   |__positive regulation of mesenchymal cell apoptotic process
                                                   |   |__positive regulation of mesenchymal cell apoptotic process involved in metanephros development(+)
                                                   |   |__positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(+)
                                                   |__positive regulation of muscle cell apoptotic process
                                                   |   |__positive regulation of smooth muscle cell apoptotic process(+)
                                                   |   |__positive regulation of striated muscle cell apoptotic process(+)
                                                   |__positive regulation of myeloid cell apoptotic process
                                                   |   |__positive regulation of erythrocyte apoptotic process
                                                   |   |__positive regulation of macrophage apoptotic process
                                                   |   |__positive regulation of mast cell apoptotic process
                                                   |   |__positive regulation of neutrophil apoptotic process
                                                   |__positive regulation of myofibroblast cell apoptotic process
                                                   |__positive regulation of neuron apoptotic process 10 rec.
                                                       |__positive regulation of hippocampal neuron apoptotic process
                                                       |__positive regulation of motor neuron apoptotic process
                                                       |__positive regulation of outer hair cell apoptotic process
                                                       |__positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
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Is a regulation of apoptotic process
positive regulation of programmed cell death
Part of
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Synonyms
  • "activation of apoptosis" NARROW
    "positive regulation of apoptosis" NARROW
    "pro-apoptosis" RELATED
    "stimulation of apoptosis" NARROW
    "up regulation of apoptosis" EXACT
    "up-regulation of apoptosis" EXACT
    "upregulation of apoptosis" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-193648 "NRAGE signals death through JNK"
Reactome:R-HSA-205043 "NRIF signals cell death from the nucleus"