FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term replication fork arrest ID (Ontology) GO:0043111 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.[ PubMed:14645529 ]
Also Known As "negative regulation of DNA replication at replication fork barrier" ; "replication fork blocking" ; "replication fork stalling"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       3
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Relevant FlyBase reports
 Genes
 replication fork arrest (all annotations which use CV term, excluding "NOT" statements)       3
     involved_in | replication fork arrest       3
Spanning Tree (Parents/Children)
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DNA metabolic process
 |__DNA-templated DNA replication maintenance of fidelity__
negative regulation of DNA replication                     |
 |__negative regulation of DNA-templated DNA replication___|
regulation of DNA-templated DNA replication                |
 |__negative regulation of DNA-templated DNA replication___|
                                                           replication fork arrest  4 rec.
                                                            |__replication fork arrest at mating type locus
                                                            |__replication fork arrest at rDNA repeats
                                                            |__replication fork arrest at tRNA locus
                                                            |__replication fork arrest involved in DNA replication termination 1 rec.
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Is a DNA-templated DNA replication maintenance of fidelity
negative regulation of DNA-templated DNA replication
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Synonyms
  • "negative regulation of DNA replication at replication fork barrier" EXACT
    "replication fork blocking" EXACT
    "replication fork stalling" EXACT
Secondary IDs
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