FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term positive regulation of protein catabolic process ID (Ontology) GO:0045732 (Gene Ontology)
Definition Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
Also Known As "positive regulation of cellular protein breakdown" ; "positive regulation of cellular protein catabolic process" ; "positive regulation of cellular protein catabolism" (for all, see Synonyms field below)
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      18
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 positive regulation of protein catabolic process (all annotations which use CV term, excluding "NOT" statements)      18
     involved_in | positive regulation of protein catabolic process      18
Spanning Tree (Parents/Children)
Only view relationship: 
positive regulation of metabolic process
 |__positive regulation of catabolic process____________
regulation of catabolic process                         |
 |__positive regulation of catabolic process____________|
 |__regulation of protein catabolic process_____________|
positive regulation of macromolecule metabolic process  |
 |__positive regulation of protein metabolic process____|
regulation of protein metabolic process                 |
 |__regulation of protein catabolic process_____________|
 |__positive regulation of protein metabolic process____|
                                                        positive regulation of protein catabolic process  68 rec.
                                                         |__positive regulation of chaperone-mediated autophagy
                                                         |__positive regulation of elastin catabolic process
                                                         |__positive regulation of low-density lipoprotein particle receptor catabolic process
                                                         |__positive regulation of membrane protein ectodomain proteolysis
                                                         |__positive regulation of proteasomal protein catabolic process 52 rec.
                                                         |   |__positive regulation of ERAD pathway 2 rec.
                                                         |   |__positive regulation of proteasomal ubiquitin-dependent protein catabolic process(+) 46 rec.
                                                         |__positive regulation of protein catabolic process in the vacuole 1 rec.
                                                         |   |__positive regulation of lysosomal protein catabolic process 1 rec.
                                                         |__positive regulation of proteolysis associated with antigen processing and presentation
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Is a positive regulation of catabolic process
regulation of protein catabolic process
positive regulation of protein metabolic process
Part of
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Synonyms
  • "activation of cellular protein breakdown" NARROW
    "activation of cellular protein catabolic process" NARROW
    "activation of cellular protein catabolism" NARROW
    "activation of cellular protein degradation" NARROW
    "activation of protein catabolic process" NARROW
    "positive regulation of cellular protein breakdown" EXACT
    "positive regulation of cellular protein catabolic process" EXACT
    "positive regulation of cellular protein catabolism" EXACT
    "positive regulation of cellular protein degradation" EXACT
    "positive regulation of cyclin breakdown" NARROW
    "positive regulation of cyclin catabolic process" NARROW
    "positive regulation of cyclin catabolism" NARROW
    "positive regulation of cyclin degradation" NARROW
    "positive regulation of degradation of cyclin" NARROW
    "positive regulation of protein breakdown" EXACT
    "positive regulation of protein catabolism" EXACT
    "positive regulation of protein degradation" EXACT
    "stimulation of protein catabolic process" NARROW
    "up regulation of cellular protein breakdown" EXACT
    "up regulation of cellular protein catabolic process" EXACT
    "up regulation of cellular protein catabolism" EXACT
    "up regulation of cellular protein degradation" EXACT
    "up regulation of protein catabolic process" EXACT
    "up-regulation of cellular protein breakdown" EXACT
    "up-regulation of cellular protein catabolic process" EXACT
    "up-regulation of cellular protein catabolism" EXACT
    "up-regulation of cellular protein degradation" EXACT
    "up-regulation of protein catabolic process" EXACT
    "upregulation of cellular protein breakdown" EXACT
    "upregulation of cellular protein catabolic process" EXACT
    "upregulation of cellular protein catabolism" EXACT
    "upregulation of cellular protein degradation" EXACT
    "upregulation of protein catabolic process" EXACT
Secondary IDs
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