General Information
Term	negative regulation of isotype switching	ID (Ontology)	GO:0045829 (Gene Ontology)
Definition	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching.
Also Known As	"down regulation of isotype switching" ; "down-regulation of isotype switching" ; "downregulation of isotype switching" (for all, see Synonyms field below)
Comment
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	QuickGO data AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
No relevant records available
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available

General Information

Term

negative regulation of isotype switching

ID (Ontology)

GO:0045829 (Gene Ontology)

Definition

Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching.

Also Known As

"down regulation of isotype switching" ; "down-regulation of isotype switching" ; "downregulation of isotype switching" (for all, see Synonyms field below)

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

regulation of DNA recombination
 |__regulation of isotype switching_________________________________________
 |__negative regulation of DNA recombination________________________________|
regulation of immunoglobulin production                                     |
 |__negative regulation of immunoglobulin production________________________|
 |__regulation of isotype switching_________________________________________|
negative regulation of production of molecular mediator of immune response  |
 |__negative regulation of immunoglobulin production________________________|
negative regulation of B cell mediated immunity                             |
 |__negative regulation of immunoglobulin mediated immune response__________|
regulation of immunoglobulin mediated immune response                       |
 |__negative regulation of immunoglobulin mediated immune response__________|
 |__regulation of isotype switching_________________________________________|
negative regulation of biological process                                   |
 |__negative regulation of developmental process____________________________|
regulation of developmental process                                         |
 |__negative regulation of developmental process____________________________|
regulation of B cell activation                                             |
 |__regulation of isotype switching_________________________________________|
 |__negative regulation of B cell activation________________________________|
negative regulation of DNA metabolic process                                |
 |__negative regulation of DNA recombination________________________________|
negative regulation of lymphocyte activation                                |
 |__negative regulation of B cell activation________________________________|
                                                                            negative regulation of isotype switching
                                                                             |__negative regulation of isotype switching to IgA isotypes
                                                                             |__negative regulation of isotype switching to IgD isotypes
                                                                             |__negative regulation of isotype switching to IgE isotypes
                                                                             |__negative regulation of isotype switching to IgG isotypes

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Relationships
Is a	negative regulation of immunoglobulin production negative regulation of immunoglobulin mediated immune response regulation of isotype switching negative regulation of DNA recombination negative regulation of B cell activation negative regulation of developmental process
Part of
Synonyms & Secondary IDs
Synonyms
	"down regulation of isotype switching" EXACT "down-regulation of isotype switching" EXACT "downregulation of isotype switching" EXACT "inhibition of isotype switching" NARROW "negative regulation of class switch recombination" EXACT "negative regulation of class switching" EXACT "negative regulation of isotype switch recombination" EXACT
Secondary IDs

External Crossreferences & Linkouts

Spanning Tree View Settings

Parents/Children
View Depth

Relationships

Is a

negative regulation of immunoglobulin production
negative regulation of immunoglobulin mediated immune response
regulation of isotype switching
negative regulation of DNA recombination
negative regulation of B cell activation
negative regulation of developmental process

Part of

Synonyms & Secondary IDs

Synonyms

"down regulation of isotype switching" EXACT
"down-regulation of isotype switching" EXACT
"downregulation of isotype switching" EXACT
"inhibition of isotype switching" NARROW
"negative regulation of class switch recombination" EXACT
"negative regulation of class switching" EXACT
"negative regulation of isotype switch recombination" EXACT

Secondary IDs

External Crossreferences & Linkouts