FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term aflatoxin metabolic process ID (Ontology) GO:0046222 (Gene Ontology)
Definition The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
Also Known As "aflatoxin metabolism"
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  toxin metabolic process
   |__mycotoxin metabolic process
       |__aflatoxin metabolic process
           |__aflatoxin biosynthetic process
           |__aflatoxin catabolic process
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Is a mycotoxin metabolic process
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Synonyms
  • "aflatoxin B metabolic process" NARROW
    "aflatoxin B1 metabolic process" RELATED
    "aflatoxin B1 metabolism" RELATED
    "aflatoxin B2 metabolic process" RELATED
    "aflatoxin B2 metabolism" RELATED
    "aflatoxin metabolism" EXACT
Secondary IDs
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Reactome:R-HSA-5423646 "Aflatoxin activation and detoxification"