FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term platelet-derived growth factor receptor signaling pathway ID (Ontology) GO:0048008 (Gene Ontology)
Definition The series of molecular signals initiated by a ligand binding to a platelet-derived growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Also Known As "PDGF receptor signaling pathway" ; "PDGF receptor signalling pathway" ; "PDGFR signaling pathway"
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  enzyme-linked receptor protein signaling pathway
   |__cell surface receptor protein tyrosine kinase signaling pathway
       |__platelet-derived growth factor receptor signaling pathway
           |__platelet-derived growth factor receptor-alpha signaling pathway
           |   |__VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway
           |__platelet-derived growth factor receptor-beta signaling pathway
           |   |__regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(+)
           |   |__VEGF-activated platelet-derived growth factor receptor-beta signaling pathway
           |__VEGF-activated platelet-derived growth factor receptor signaling pathway
               |__positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signaling pathway
               |__positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
               |__VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway
               |__VEGF-activated platelet-derived growth factor receptor-beta signaling pathway
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Is a cell surface receptor protein tyrosine kinase signaling pathway
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Synonyms
  • "PDGF receptor signaling pathway" EXACT
    "PDGF receptor signalling pathway" EXACT
    "PDGFR signaling pathway" EXACT
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