FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term regulation of protein secretion ID (Ontology) GO:0050708 (Gene Ontology)
Definition Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       3
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 regulation of protein secretion (all annotations which use CV term, excluding "NOT" statements)       3
     involved_in | regulation of protein secretion       3
Spanning Tree (Parents/Children)
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regulation of cellular process
 |__regulation of secretion by cell__________________
regulation of secretion                              |
 |__regulation of secretion by cell__________________|
regulation of transport                              |
 |__regulation of protein transport__________________|
regulation of establishment of protein localization  |
 |__regulation of protein transport__________________|
                                                     regulation of protein secretion  25 rec.
                                                      |__negative regulation of protein secretion 4 rec.
                                                      |   |__negative regulation of adiponectin secretion
                                                      |   |__negative regulation of BMP secretion
                                                      |   |__negative regulation of insulin secretion(+) 1 rec.
                                                      |   |__negative regulation of matrix metallopeptidase secretion
                                                      |   |__negative regulation of pancreatic amylase secretion
                                                      |   |__negative regulation of pancreatic trypsinogen secretion
                                                      |   |__negative regulation of prolactin secretion
                                                      |   |__negative regulation of renin secretion into blood stream
                                                      |   |__negative regulation of secretion of lysosomal enzymes
                                                      |   |__negative regulation of Wnt protein secretion 1 rec.
                                                      |__positive regulation of protein secretion 17 rec.
                                                      |   |__positive regulation of adiponectin secretion
                                                      |   |__positive regulation of BMP secretion
                                                      |   |__positive regulation of insulin secretion(+) 6 rec.
                                                      |   |__positive regulation of matrix metallopeptidase secretion
                                                      |   |__positive regulation of pancreatic amylase secretion(+)
                                                      |   |__positive regulation of pancreatic trypsinogen secretion
                                                      |   |__positive regulation of prolactin secretion
                                                      |   |__positive regulation of renin secretion into blood stream
                                                      |   |__positive regulation of secretion of lysosomal enzymes
                                                      |   |__positive regulation of Wnt protein secretion 6 rec.
                                                      |__regulation of adiponectin secretion
                                                      |   |__negative regulation of adiponectin secretion
                                                      |   |__positive regulation of adiponectin secretion
                                                      |__regulation of BMP secretion
                                                      |   |__negative regulation of BMP secretion
                                                      |   |__positive regulation of BMP secretion
                                                      |__regulation of insulin secretion 8 rec.
                                                      |   |__negative regulation of insulin secretion(+) 1 rec.
                                                      |   |__positive regulation of insulin secretion(+) 6 rec.
                                                      |   |__regulation of insulin secretion involved in cellular response to glucose stimulus(+)
                                                      |__regulation of matrix metallopeptidase secretion
                                                      |   |__negative regulation of matrix metallopeptidase secretion
                                                      |   |__positive regulation of matrix metallopeptidase secretion
                                                      |__regulation of pancreatic amylase secretion
                                                      |   |__negative regulation of pancreatic amylase secretion
                                                      |   |__positive regulation of pancreatic amylase secretion(+)
                                                      |__regulation of pancreatic trypsinogen secretion
                                                      |   |__negative regulation of pancreatic trypsinogen secretion
                                                      |   |__positive regulation of pancreatic trypsinogen secretion
                                                      |__regulation of renin secretion into blood stream
                                                      |   |__negative regulation of renin secretion into blood stream
                                                      |   |__positive regulation of renin secretion into blood stream
                                                      |__regulation of secretion of lysosomal enzymes
                                                      |   |__negative regulation of secretion of lysosomal enzymes
                                                      |   |__positive regulation of secretion of lysosomal enzymes
                                                      |__regulation of Wnt protein secretion 7 rec.
                                                          |__negative regulation of Wnt protein secretion 1 rec.
                                                          |__positive regulation of Wnt protein secretion 6 rec.
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Is a regulation of protein transport
regulation of secretion by cell
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