FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term negative regulation of T cell activation ID (Ontology) GO:0050868 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.
Also Known As "down regulation of T cell activation" ; "down-regulation of T cell activation" ; "downregulation of T cell activation" (for all, see Synonyms field below)
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negative regulation of leukocyte activation
 |__negative regulation of lymphocyte activation_________
negative regulation of cell-cell adhesion                |
 |__negative regulation of leukocyte cell-cell adhesion__|
regulation of lymphocyte activation                      |
 |__regulation of T cell activation______________________|
 |__negative regulation of lymphocyte activation_________|
regulation of leukocyte cell-cell adhesion               |
 |__negative regulation of leukocyte cell-cell adhesion__|
                                                         negative regulation of T cell activation
                                                          |__negative regulation of alpha-beta T cell activation
                                                          |   |__negative regulation of alpha-beta T cell differentiation(+)
                                                          |   |__negative regulation of alpha-beta T cell proliferation(+)
                                                          |   |__negative regulation of CD4-positive, alpha-beta T cell activation(+)
                                                          |   |__negative regulation of CD8-positive, alpha-beta T cell activation(+)
                                                          |   |__negative regulation of NK T cell activation(+)
                                                          |__negative regulation of establishment of T cell polarity
                                                          |__negative regulation of gamma-delta T cell activation
                                                          |   |__negative regulation of gamma-delta T cell activation involved in immune response
                                                          |   |__negative regulation of gamma-delta T cell differentiation
                                                          |   |__negative regulation of gamma-delta T cell proliferation
                                                          |__negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
                                                          |__negative regulation of T cell differentiation
                                                          |   |__negative regulation of alpha-beta T cell differentiation(+)
                                                          |   |__negative regulation of cytotoxic T cell differentiation
                                                          |   |__negative regulation of extrathymic T cell differentiation
                                                          |   |__negative regulation of gamma-delta T cell differentiation
                                                          |   |__negative regulation of memory T cell differentiation
                                                          |   |__negative regulation of pro-T cell differentiation
                                                          |   |__negative regulation of regulatory T cell differentiation(+)
                                                          |   |__negative regulation of T cell differentiation in thymus(+)
                                                          |__negative regulation of T cell proliferation
                                                              |__negative regulation of activated T cell proliferation
                                                              |__negative regulation of alpha-beta T cell proliferation(+)
                                                              |__negative regulation of gamma-delta T cell proliferation
                                                              |__negative regulation of immature T cell proliferation(+)
                                                              |__negative regulation of T cell homeostatic proliferation
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Is a regulation of T cell activation
negative regulation of lymphocyte activation
negative regulation of leukocyte cell-cell adhesion
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Synonyms
  • "down regulation of T cell activation" EXACT
    "down-regulation of T cell activation" EXACT
    "downregulation of T cell activation" EXACT
    "inhibition of T cell activation" NARROW
    "negative regulation of T lymphocyte activation" EXACT
    "negative regulation of T-cell activation" EXACT
    "negative regulation of T-lymphocyte activation" EXACT
Secondary IDs
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