FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term negative regulation of DNA metabolic process ID (Ontology) GO:0051053 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.
Also Known As "down regulation of DNA metabolic process" ; "down-regulation of DNA metabolic process" ; "downregulation of DNA metabolic process" (for all, see Synonyms field below)
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negative regulation of metabolic process
 |__negative regulation of macromolecule metabolic process___________________
 |__negative regulation of nucleobase-containing compound metabolic process__|
regulation of nucleobase-containing compound metabolic process               |
 |__negative regulation of nucleobase-containing compound metabolic process__|
 |__regulation of DNA metabolic process______________________________________|
regulation of macromolecule metabolic process                                |
 |__negative regulation of macromolecule metabolic process___________________|
 |__regulation of DNA metabolic process______________________________________|
                                                                             negative regulation of DNA metabolic process  44 rec.
                                                                              |__negative regulation of DNA biosynthetic process
                                                                              |   |__negative regulation of DNA amplification
                                                                              |   |__negative regulation of error-prone translesion synthesis
                                                                              |   |__negative regulation of reverse transcription
                                                                              |   |__negative regulation of telomere maintenance via telomerase
                                                                              |__negative regulation of DNA catabolic process
                                                                              |   |__negative regulation of apoptotic DNA fragmentation
                                                                              |__negative regulation of DNA recombination 28 rec.
                                                                              |   |__inactivation of recombination (HML)
                                                                              |   |__negative regulation of DNA recombination at centromere
                                                                              |   |__negative regulation of DNA recombination at telomere(+)
                                                                              |   |__negative regulation of double-strand break repair via homologous recombination(+)
                                                                              |   |__negative regulation of isotype switching(+)
                                                                              |   |__negative regulation of mitotic recombination(+) 3 rec.
                                                                              |   |__negative regulation of reciprocal meiotic recombination
                                                                              |   |__negative regulation of single-strand break repair via homologous recombination
                                                                              |   |__negative regulation of strand invasion
                                                                              |__negative regulation of DNA repair 2 rec.
                                                                              |   |__negative regulation of base-excision repair
                                                                              |   |__negative regulation of double-strand break repair(+) 2 rec.
                                                                              |   |__negative regulation of mismatch repair
                                                                              |   |__negative regulation of single strand break repair(+)
                                                                              |__negative regulation of DNA replication 14 rec.
                                                                              |   |__negative regulation of DNA-templated DNA replication(+) 8 rec.
                                                                              |__negative regulation of meiotic DNA double-strand break formation
                                                                              |   |__negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination
                                                                              |__negative regulation of mitochondrial DNA metabolic process 1 rec.
                                                                              |   |__negative regulation of mitochondrial DNA replication 1 rec.
                                                                              |__negative regulation of mitotic recombination-dependent replication fork processing
                                                                              |__negative regulation of t-circle formation 1 rec.
                                                                              |__negative regulation of telomere maintenance
                                                                                  |__negative regulation of telomere capping(+)
                                                                                  |__negative regulation of telomere maintenance in response to DNA damage(+)
                                                                                  |__negative regulation of telomere maintenance via recombination
                                                                                  |__negative regulation of telomere maintenance via semi-conservative replication
                                                                                  |__negative regulation of telomere maintenance via telomere lengthening(+)
                                                                                  |__negative regulation of telomeric loop disassembly(+)
                                                                                  |__negative regulation of telomeric loop formation
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Is a negative regulation of macromolecule metabolic process
negative regulation of nucleobase-containing compound metabolic process
regulation of DNA metabolic process
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Synonyms
  • "down regulation of DNA metabolic process" EXACT
    "down-regulation of DNA metabolic process" EXACT
    "downregulation of DNA metabolic process" EXACT
    "inhibition of DNA metabolic process" NARROW
    "negative regulation of DNA metabolism" EXACT
Secondary IDs
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