FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term regulation of macromolecule metabolic process ID (Ontology) GO:0060255 (Gene Ontology)
Definition Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
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Spanning Tree (Parents/Children)
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  regulation of cellular process
   |__regulation of metabolic process
       |__regulation of macromolecule metabolic process  2209 rec.
           |__negative regulation of macromolecule metabolic process 1000 rec.
           |   |__negative regulation of cell wall polysaccharide catabolic process(+)
           |   |__negative regulation of cellodextrin catabolic process
           |   |__negative regulation of cellulose catabolic process
           |   |__negative regulation of cyclodextrin catabolic process
           |   |__negative regulation of DNA metabolic process(+) 44 rec.
           |   |__negative regulation of galactoglucomannan catabolic process
           |   |__negative regulation of galactomannan catabolic process
           |   |__negative regulation of glucomannan catabolic process
           |   |__negative regulation of glycogen metabolic process(+) 4 rec.
           |   |__negative regulation of hemicellulose catabolic process(+)
           |   |__negative regulation of macromolecule biosynthetic process(+) 929 rec.
           |   |__negative regulation of pectin catabolic process
           |   |__negative regulation of protein metabolic process(+) 140 rec.
           |   |__negative regulation of receptor catabolic process(+)
           |   |__negative regulation of receptor recycling 3 rec.
           |   |__negative regulation of RNA metabolic process(+) 340 rec.
           |   |__negative regulation of starch catabolic process(+)
           |__positive regulation of macromolecule metabolic process 816 rec.
           |   |__positive regulation of cell wall polysaccharide catabolic process(+)
           |   |__positive regulation of cellodextrin catabolic process
           |   |__positive regulation of cellulose catabolic process
           |   |__positive regulation of cyclodextrin catabolic process
           |   |__positive regulation of DNA metabolic process(+) 24 rec.
           |   |__positive regulation of galactoglucomannan catabolic process
           |   |__positive regulation of galactomannan catabolic process
           |   |__positive regulation of glycogen metabolic process(+) 14 rec.
           |   |__positive regulation of hemicellulose catabolic process(+)
           |   |__positive regulation of macromolecule biosynthetic process(+) 630 rec.
           |   |__positive regulation of pectin catabolic process
           |   |__positive regulation of protein metabolic process(+) 149 rec.
           |   |__positive regulation of receptor catabolic process(+)
           |   |__positive regulation of receptor recycling 1 rec.
           |   |__positive regulation of RNA metabolic process(+) 526 rec.
           |   |__positive regulation of starch catabolic process(+)
           |__regulation of amylopectin catabolic process
           |   |__negative regulation of amylopectin catabolic process
           |   |__positive regulation of amylopectin catabolic process
           |__regulation of cell wall macromolecule metabolic process
           |   |__regulation of cell wall (1->3)-alpha-glucan biosynthetic process(+)
           |   |__regulation of cell wall (1->3)-beta-D-glucan biosynthetic process(+)
           |   |__regulation of cell wall polysaccharide catabolic process(+)
           |   |__regulation of fungal-type cell wall beta-glucan biosynthetic process(+)
           |   |__regulation of plant-type cell wall cellulose biosynthetic process(+)
           |__regulation of DNA metabolic process 83 rec.
           |   |__negative regulation of DNA metabolic process(+) 44 rec.
           |   |__positive regulation of DNA metabolic process(+) 24 rec.
           |   |__regulation of DNA biosynthetic process(+) 2 rec.
           |   |__regulation of DNA catabolic process(+)
           |   |__regulation of DNA double-strand break processing 1 rec.
           |   |__regulation of DNA recombination(+) 32 rec.
           |   |__regulation of DNA repair(+) 17 rec.
           |   |__regulation of DNA replication(+) 32 rec.
           |   |__regulation of DNA strand elongation(+)
           |   |__regulation of DNA strand resection involved in replication fork processing(+)
           |   |__regulation of meiotic DNA double-strand break formation(+) 3 rec.
           |   |__regulation of mitochondrial DNA metabolic process(+) 4 rec.
           |   |__regulation of mitotic recombination-dependent replication fork processing(+)
           |   |__regulation of strand invasion(+)
           |   |__regulation of telomere maintenance(+) 3 rec.
           |__regulation of macromolecule biosynthetic process 2002 rec.
           |   |__negative regulation of macromolecule biosynthetic process(+) 929 rec.
           |   |__positive regulation of macromolecule biosynthetic process(+) 630 rec.
           |   |__regulation of cutin biosynthetic process(+)
           |   |__regulation of DNA biosynthetic process(+) 2 rec.
           |   |__regulation of gene expression(+) 1988 rec.
           |   |__regulation of glycoprotein biosynthetic process(+) 3 rec.
           |   |__regulation of hemoglobin biosynthetic process(+)
           |   |__regulation of integrin biosynthetic process(+)
           |   |__regulation of MHC class I biosynthetic process(+)
           |   |__regulation of MHC class II biosynthetic process(+)
           |   |__regulation of polysaccharide biosynthetic process(+) 8 rec.
           |   |__regulation of protein geranylgeranylation(+)
           |   |__regulation of protein lipidation(+)
           |   |__regulation of RNA biosynthetic process(+) 1176 rec.
           |   |__regulation of sphingolipid biosynthetic process(+) 4 rec.
           |__regulation of phosphatidylinositol dephosphorylation
           |__regulation of polysaccharide metabolic process 22 rec.
           |   |__regulation of alpha-glucan metabolic process(+)
           |   |__regulation of beta-glucan metabolic process(+)
           |   |__regulation of cell wall pectin metabolic process
           |   |__regulation of cell wall polysaccharide catabolic process(+)
           |   |__regulation of cellodextrin catabolic process(+)
           |   |__regulation of chitin metabolic process(+)
           |   |__regulation of cyclodextrin catabolic process(+)
           |   |__regulation of galactoglucomannan catabolic process(+)
           |   |__regulation of galactomannan catabolic process(+)
           |   |__regulation of glucomannan catabolic process(+)
           |   |__regulation of glycogen metabolic process(+) 22 rec.
           |   |__regulation of hemicellulose catabolic process(+)
           |   |__regulation of pectin catabolic process(+)
           |   |__regulation of polysaccharide biosynthetic process(+) 8 rec.
           |   |__regulation of starch metabolic process(+)
           |__regulation of protein metabolic process 347 rec.
           |   |__negative regulation of protein metabolic process(+) 140 rec.
           |   |__positive regulation of protein metabolic process(+) 149 rec.
           |   |__regulation of amyloid fibril formation(+)
           |   |__regulation of amyloid precursor protein catabolic process(+) 1 rec.
           |   |__regulation of angiotensin metabolic process
           |   |__regulation of glycoprotein metabolic process(+) 3 rec.
           |   |__regulation of granulocyte macrophage colony-stimulating factor production(+)
           |   |__regulation of hemoglobin biosynthetic process(+)
           |   |__regulation of hepatocyte growth factor production(+)
           |   |__regulation of lipoprotein metabolic process(+)
           |   |__regulation of lymphotoxin A production(+)
           |   |__regulation of protein catabolic process(+) 91 rec.
           |   |__regulation of protein maturation(+) 10 rec.
           |   |__regulation of protein modification process(+) 42 rec.
           |   |__regulation of proteolysis(+) 121 rec.
           |   |__regulation of translation(+) 169 rec.
           |__regulation of receptor catabolic process
           |   |__negative regulation of receptor catabolic process(+)
           |   |__positive regulation of receptor catabolic process(+)
           |   |__regulation of low-density lipoprotein particle receptor catabolic process(+)
           |__regulation of receptor recycling 5 rec.
           |   |__negative regulation of receptor recycling 3 rec.
           |   |__positive regulation of receptor recycling 1 rec.
           |__regulation of RNA metabolic process 1356 rec.
               |__negative regulation of RNA metabolic process(+) 340 rec.
               |__positive regulation of RNA metabolic process(+) 526 rec.
               |__regulation of miRNA metabolic process(+) 2 rec.
               |__regulation of mitochondrial RNA catabolic process(+) 2 rec.
               |__regulation of mRNA metabolic process(+) 191 rec.
               |__regulation of ribonuclease activity(+)
               |__regulation of RNA biosynthetic process(+) 1176 rec.
               |__regulation of RNA stability(+) 89 rec.
               |__regulation of rRNA catabolic process(+)
               |__regulation of rRNA processing(+) 2 rec.
               |__regulation of snoRNA metabolic process(+)
               |__regulation of snRNA pseudouridine synthesis(+)
               |__regulation of tRNA metabolic process(+) 3 rec.
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