FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term prespliceosome ID (Ontology) GO:0071010 (Gene Ontology)
Definition A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex.[ PubMed:17332742 PubMed:19239890 ]
Also Known As "prespliceosomal complex"
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nuclear protein-containing complex__
ribonucleoprotein complex___________|
                                    spliceosomal complex
                                     |__prespliceosome  15 rec.
                                         |__U2-type prespliceosome 15 rec.
                                         |__U12-type prespliceosome
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Is a spliceosomal complex
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Synonyms
  • "mammalian spliceosomal complex A" NARROW[ ISBN:0879695897 ISBN:0879697393 PubMed:19239890 ]
    "prespliceosomal complex" EXACT
    "yeast spliceosomal complex B" NARROW[ ISBN:0879695897 ISBN:0879697393 ]
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