FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term constitutive heterochromatin formation ID (Ontology) GO:0140719 (Gene Ontology)
Definition The compaction of chromatin into heterochromatin, a conformation that is refractory to transcription. Constitutive heterochromatin cannot be converted back to euchromatin, the transcriptionally-active conformation. In metazoa, this involves the methylation of histone H3K9.[ PubMed:17936700 ]
Also Known As "constitutive heterochromatin assembly"
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
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 Genes
 constitutive heterochromatin formation (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | constitutive heterochromatin formation       1
Spanning Tree (Parents/Children)
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cellular component assembly_________________________
negative regulation of gene expression, epigenetic__|
heterochromatin organization________________________|
                                                    heterochromatin formation
                                                     |__constitutive heterochromatin formation  41 rec.
                                                         |__DNA methylation-dependent constitutive heterochromatin formation 2 rec.
                                                         |   |__gene silencing by piRNA-directed DNA methylation(+)
                                                         |   |__gene silencing by siRNA-directed DNA methylation(+)
                                                         |__pericentric heterochromatin formation 7 rec.
                                                         |   |__siRNA-mediated pericentric heterochromatin formation 2 rec.
                                                         |__silent mating-type cassette heterochromatin formation
                                                         |   |__siRNA-mediated silent mating type cassette region heterochromatin formation
                                                         |__subtelomeric heterochromatin formation 7 rec.
                                                         |__transposable element silencing by heterochromatin formation 29 rec.
                                                             |__transposable element silencing by piRNA-mediated DNA methylation
                                                             |__transposable element silencing by piRNA-mediated heterochromatin formation 20 rec.
                                                             |__transposable element silencing by siRNA-mediated DNA methylation
                                                             |__transposable element silencing by siRNA-mediated heterochromatin formation
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