FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term intracellular signaling cassette ID (Ontology) GO:0141124 (Gene Ontology)
Definition An intracellular signaling module that is part of larger signaling pathways that can be initiated either intracellularly or by cell surface receptors. Intracellular signaling cassettes are discrete signaling units that are often shared by multiple signaling pathways.
Also Known As "intracellular signaling cascade" ; "intracellular signaling module"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available
Spanning Tree (Parents/Children)
Only view relationship:
  signal transduction
   |__intracellular signal transduction
       |__intracellular signaling cassette  428 rec.
           |__calcium-mediated signaling 34 rec.
           |   |__calcineurin-mediated signaling(+) 12 rec.
           |   |__CAMKK-AMPK signaling cascade 1 rec.
           |   |__regulation of cardiac muscle contraction by calcium ion signaling(+) 2 rec.
           |   |__regulation of skeletal muscle contraction by calcium ion signaling(+)
           |__cAMP/PKA signal transduction 8 rec.
           |__canonical NF-kappaB signal transduction 13 rec.
           |__integrated stress response signaling 2 rec.
           |   |__GCN2-mediated signaling
           |   |__HRI-mediated signaling
           |   |__PERK-mediated unfolded protein response 2 rec.
           |   |__PKR/eIFalpha signaling
           |__MAPK cascade 167 rec.
           |   |__ERK1 and ERK2 cascade 49 rec.
           |   |__ERK5 cascade
           |   |__JNK cascade 86 rec.
           |   |__p38MAPK cascade 8 rec.
           |   |__pheromone response MAPK cascade
           |   |__stress-activated MAPK cascade(+) 5 rec.
           |__nitric oxide mediated signal transduction 5 rec.
           |   |__nitric oxide-cGMP-mediated signaling 4 rec.
           |__non-canonical NF-kappaB signal transduction 3 rec.
           |__phosphatidylinositol 3-kinase/protein kinase B signal transduction 33 rec.
           |__phospholipase C/protein kinase C signal transduction
           |__SMAD protein signal transduction 11 rec.
           |__small GTPase-mediated signal transduction 194 rec.
               |__ARF protein signal transduction 10 rec.
               |__Rab protein signal transduction 52 rec.
               |__Rac protein signal transduction 9 rec.
               |__Ral protein signal transduction 3 rec.
               |__Ran protein signal transduction
               |__Rap protein signal transduction 5 rec.
               |__Ras protein signal transduction 49 rec.
               |__Rho protein signal transduction(+) 41 rec.
               |__septation initiation signaling
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a intracellular signal transduction
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "intracellular signaling cascade" EXACT
    "intracellular signaling module" EXACT
Secondary IDs
hide External Crossreferences & Linkouts