FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term regulation of signal transduction by p53 class mediator ID (Ontology) GO:1901796 (Gene Ontology)
Definition Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.
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  regulation of signal transduction
   |__regulation of intracellular signal transduction
       |__regulation of signal transduction by p53 class mediator  5 rec.
           |__negative regulation of signal transduction by p53 class mediator 2 rec.
           |   |__negative regulation of DNA damage response, signal transduction by p53 class mediator 1 rec.
           |   |__negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(+) 2 rec.
           |__positive regulation of signal transduction by p53 class mediator 2 rec.
           |   |__positive regulation of DNA damage response, signal transduction by p53 class mediator 1 rec.
           |   |__positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(+) 1 rec.
           |__regulation of DNA damage response, signal transduction by p53 class mediator 3 rec.
           |   |__negative regulation of DNA damage response, signal transduction by p53 class mediator 1 rec.
           |   |__positive regulation of DNA damage response, signal transduction by p53 class mediator 1 rec.
           |__regulation of intrinsic apoptotic signaling pathway by p53 class mediator 3 rec.
               |__negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(+) 2 rec.
               |__positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(+) 1 rec.
               |__regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(+) 3 rec.
               |__regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator(+)
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Is a regulation of intracellular signal transduction
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Reactome:R-HSA-5633007 "Regulation of TP53 Activity"