FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term positive regulation of intrinsic apoptotic signaling pathway ID (Ontology) GO:2001244 (Gene Ontology)
Definition Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.
Also Known As "positive regulation of intrinsic apoptotic pathway" ; "positive regulation of intrinsic apoptotic signalling pathway" ; "positive regulation of mitochondrial-mediated apoptotic pathway"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 positive regulation of intrinsic apoptotic signaling pathway (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | positive regulation of intrinsic apoptotic signaling pathway       1
Spanning Tree (Parents/Children)
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positive regulation of signal transduction
 |__positive regulation of intracellular signal transduction__
 |__positive regulation of apoptotic signaling pathway________|
positive regulation of apoptotic process                      |
 |__positive regulation of apoptotic signaling pathway________|
regulation of intracellular signal transduction               |
 |__positive regulation of intracellular signal transduction__|
 |__regulation of intrinsic apoptotic signaling pathway_______|
regulation of apoptotic signaling pathway                     |
 |__positive regulation of apoptotic signaling pathway________|
 |__regulation of intrinsic apoptotic signaling pathway_______|
                                                              positive regulation of intrinsic apoptotic signaling pathway  3 rec.
                                                               |__positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1 rec.
                                                               |__positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1 rec.
                                                               |   |__positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1 rec.
                                                               |   |__positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
                                                               |__positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage 1 rec.
                                                               |   |__positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1 rec.
                                                               |__positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
                                                               |   |__positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
                                                               |__positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
                                                               |__positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
                                                                   |__positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
                                                                   |__positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
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Is a positive regulation of intracellular signal transduction
positive regulation of apoptotic signaling pathway
regulation of intrinsic apoptotic signaling pathway
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Synonyms
  • "positive regulation of intrinsic apoptosis" NARROW
    "positive regulation of intrinsic apoptotic pathway" EXACT
    "positive regulation of intrinsic apoptotic signalling pathway" EXACT
    "positive regulation of mitochondrial-mediated apoptotic pathway" EXACT
Secondary IDs
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Reactome:R-HSA-111453 "BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members"