FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\N264-103
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General Information
Symbol
Dmel\N264-103
Species
D. melanogaster
Name
FlyBase ID
FBal0012754
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Progenitor genotype
Cytology

Polytene chromosomes appear normal.

Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Male flies carrying Dp(1;2)51bV76e show wing-notching and lateral incisions, leg defects and tarsal reductions, missing or multiple bristles, missing or fused ocelli and variegated or roughened eyes, at varying frequencies.

N264-103/Nnd-3 females survive when raised at 22oC but die at 29oC. One or several temperature sensitive periods (TSPs) for lethality occur during the embryonic, larval and prepupal-pupal stages (either a single TSP for lethality begins in the embryos stage and lasts into the pupal stage or there are several discrete TSPs). N264-103/Nspl-1 flies show wing nicking and tarsal segment fusion phenotypes and also show the Nspl-1 eye phenotype. The mutant eye and wing phenotypes are more strongly expressed at high temperatures than low temperatures, and tarsal fusion only occurs at high temperatures. At 20-22oC, the eyes approach wild type but usually contain small, irregularly positioned areas of facet disarray, while at 28-29oC the facet disarray extends over the whole surface of the eye. The temperature sensitive periods of these phenotypes occur during the third larval instar stage.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Demerec, Jan. 1940.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (4)