biz^SB8/biz^SB8 flies are thermoblind (23-45[o]C). biz^SB8/biz^SB8 flies show jump latencies similar to wild type in a CO[2] laser beam assay (can sense noxious thermal stimuli and thermal nociception induces a jump response) but show a significant increase in jump latency in a heat plate assay.

Homozygous flies are extremely sluggish. Heterozygous flies have a reduced thermosensitivity at the low end, but are normal in their ability to detect temperature differences (3^o or 6^oC) in the range of their thermosensitivity. In a "heat-box" learning paradigm, heterozygous flies show no significant avoidance behaviour or memory when using a 37^oC punishment temperature.

Shows mutant temperature gradient response, in having no temperature preference. Flies are completely thermoblind. They are also blind to humidity.