FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\snvw
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General Information
Symbol
Dmel\snvw
Species
D. melanogaster
Name
very weak
FlyBase ID
FBal0062440
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Associated Insertion(s)
Cytology
Description

Insertion of a 650bp internally deleted P-element (all base pairs between 204 and 2500 are deleted). This P-element is inserted adjacent to the P{KP} element present in the progenitor (snBL6) in the 5' non-coding exon of sn, at base pairs 2647 to 2654. The two P-elements are inserted in a tail-to-tail orientation.

Insertion of 0.65kb DNA, very close to the P-element present in the progenitor (snBL6). The restriction map of the 0.65kb fragment is consistent with it being part of a P-element.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
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Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
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Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Partial revertant; phenotype is almost wild-type, although there are patches of sn bristles. Somatic reversion of this allele, generating patches with a strong sn phenotype, occurs at a relatively high frequency.

External Data
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Phenotypic Class
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Genetic Interactions
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Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Unstable allele; can revert to a strong sn phenotype in germ cells. Appreciable somatic reversion of this allele, generating mosaics having patches with a strong sn phenotype, is also seen. The movements of the P-elements in these somatic reversions occur early in development, and require a trans-acting maternal effect component (P\TMo). Somatic reversion occurs preferentially in attached-X stocks.

The majority of germline revertants of snvw show either a strong sn phenotype or are wild-type. Revertants with a strong sn phenotype appear to result from precise excision of the smaller of the two P-element insertions present in snvw. Wild-type revertants appear to result from precise excision of the larger of the two P-element insertions present in snvw. Somatic reversion of snvw (in males derived from mothers carrying P\TMo) is caused by excision of the smaller of the two P-element insertions present in snvw.

The rate of somatic reversion (mosaicism) in snvw flies derived from females carrying P\TMo has been studied. The rate of somatic reversion is reduced threefold if the mother also carries snvw.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
snvw
Name Synonyms
Secondary FlyBase IDs
    References (3)