FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\l(2)k10209k10209
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General Information
Symbol
Dmel\l(2)k10209k10209
Species
D. melanogaster
Name
FlyBase ID
FBal0064219
Feature type
allele
Associated gene
l(2)k10209
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(BDGP Project Members, 1994-1999)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes show significant lethality during all stages examined (embryogenesis to pharate adult). Some homozygous adults are able to eclose, but they die 2 to 3 days later. Homozygous pharate adults have malformed legs which may fail to extend to the tip of the abdomen but remain organised. The femur may contain constrictions. 91% of mutant mid-prepupae have at least one malformed leg, 94% of mutant pupae and adults have at least one malformed leg.

      (Gates and Thummel, 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      I. Kiss.

      (BDGP Project Members, 1994-1999)

      Separable from: CG6426k10209. The lethality of the "l(2)k10209" chromosome (caused by l(2)k10209k10209) is separable from the P{lacW}CG6426k10209 insertion.

      (Spradling, 1999.12.9)

      Separable from: P{lacW}CG6426k10209. The P{lacW}CG6426k10209 insertion in the "l(2)k10209" line is separable from the mutation causing the lethality and malformed leg phenotypes (l(2)k10209k10209).

      (Gates and Thummel, 2000)
      Comments
      Comments

      This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu).

      Complements: l(2)k04810k04810. Complements: l(2)k05421k05421. Complements: vegk07202.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      l(2)k10209k10209
      Name Synonyms
      Secondary FlyBase IDs
        References (3)