FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\knKN1
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General Information
Symbol
Dmel\knKN1
Species
D. melanogaster
Name
FlyBase ID
FBal0082869
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Embryonic segmentation is normal. Transheterozygotes with kn1 enhance the kn1 wing vein phenotype, the veins are extensively fused. This loss of intervein region reduced the length and width of the wings by 80-90%. The transition point between socketed and unsocketed bristles at the wing margin is shifted posteriorly to the shifted position of wing vein L3. Germline clones give rise to fully viable offspring when outcrossed to kn+ sperm and does not alter the larval lethality when fertilised with knKN1, knKN2, knKN3 or knKN4 sperm. Clones generated in adult cuticle are normal unless induced in the anterior compartment of the wing in the intervein region between veins L3 and L4. Clones obey the A-P compartment boundary but when they are induced along the boundary the result is an ectopic or shifted vein with an associated loss of vein L4 in the non-mutant posterior compartment. Clones located at the wing margin generated terminal vein 3 bristles rather than true marginal bristles.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
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Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
knKN1
Name Synonyms
Secondary FlyBase IDs
    References (1)