FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Fs(2)11
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General Information
Symbol
Dmel\Fs(2)11
Species
D. melanogaster
Name
FlyBase ID
FBal0089706
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Fs(2)1
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology

Polytene chromosomes normal.

Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Heterozygous females deposit few, mostly flaccid eggs that do not have dorsal chorionic appendages.

Germ line-dependent female sterile.

The dominant female sterile phenotype of Fs(2)11 is fully penetrant and expressive. Fs(2)11 has no affect on the rate of development or on male fertility. Heterozygous females produce 0-4 eggs per day, which usually collapse after deposition. The dorsal appendages are missing, and the anterior part of the egg is often not covered with chorion. Egg primordia develop normally up to stages 8-10, but then pyknosis of the nurse cell nuclei is seen, chorion defects develop and 90-95% of the egg primordia are resorbed. Heterozygous ovaries transplanted into wild-type hosts show the mutant phenotype, while wild-type ovaries transplanted into heterozygous females develop normally, indicating that the Fs(2)11 phenotype is ovary autonomous.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Germ line clonal analysis indicates that Fs(2)11 is germ line-dependent.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (3)