FB2025_01 , released February 20, 2025
Allele: Dmel\mys::torD.UAS
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General Information
Symbol
Dmel\mys::torD.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0096746
Feature type
allele
Associated gene
mys::tor
Associated Insertion(s)
Carried in Construct
P{UAS-mys::tor.D}
Also Known As
UAS-torsoD/βcyt
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Martin-Bermudo and Brown, 1999)
Progenitor genotype
Carried in construct
P{UAS-mys::tor.D}
Cytology
Description

UAS regulatory sequences drive expression of a chimeric construct consisting of the extracellular and transmembrane domains of tor13D fused to the cytoplasmic domain of mys.

(Martin-Bermudo and Brown, 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
mys::tor
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of mys::torD.Scer\UAS in the wing under the control of Scer\GAL469B results in a wing-blister phenotype.

      (Tanentzapf et al., 2006)

      When mys::torD.Scer\UAS is driven un the amnioserosa (by Scer\GAL4c381) or the yolk (by Scer\GAL4P0180), separation between amnioserosa and yolk membrane, and thining of the amnioserosa is seen. Expression also causes a strong reduction of the amnioserosa/leading edge interface and rips in the amnioserosa. 11% of embryos have dorsal holes. When mys::torD.Scer\UAS is driven in the yolk (by Scer\GAL4P0180), separation between amnioserosa and yolk membrane, and thining of the amnioserosa is seen. 6% of embryos have dorsal holes. When mys::torD.Scer\UAS is driven in both the amnioserosa and yolk (Scer\GAL4P0181) 38% of embryos have dorsal holes.

      (Narasimha and Brown, 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mys::torD.Scer\UAS
      mys::torD.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (11)