Homozygous Dic61Bf07138 mutants show developmental delay and eclose 24 to 36 hours later than wild type. This phenotype is seen at both 22[o]C and 25[o]C. Furthermore about 70% of Dic61Bf07138 flies show moderate to severe defects in the formation of the dorsal abdominal tergites and ventral sternites.
Dic61Bf07138 mutants exhibit pupal lethality when raised at 29[o]C. Approximately 18% of homozygotes and 60% of heterozygotes eclose as flies.
Dic61Bf07138 mutant testes are packed with abnormally bent sperm bundles, making the testes bulge slightly in the middle region and displacing all other cell types from their orderly arrangement. The individualisation complexes are well-organised, but actin cones appear disrupted soon after commencing the journey towards the caudal end of sperm tails and degrade prematurely in the middle region of the testis, before the sperm are individualised.
Dic61Bf07138 fails to complement the male sterile phenotype seen in Dic61Bms21.
Dic61Bf07138 fails to complement the male sterile phenotype seen in either Df(3L)ED201 or Df(3L)Exel6083.
Precise excision of the PBac{WH} transposon in PBac{WH}Dic61Bf07138 rescues the male sterility.