FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mxte00436
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General Information
Symbol
Dmel\mxte00436
Species
D. melanogaster
Name
FlyBase ID
FBal0186574
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description

Insertion in the 5' UTR.

Allele components
Component
Use(s)
Inserted element
Mutations Mapped to the Genome
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

21.3% of eggs laid by mxte00436/Df(2L)Exel6010 females mated to wild-type males fail to hatch. The embryos that fail to hatch show variable segmentation defects including deletion of one or more thoracic or abdominal segments, severe global defects or malformation or incomplete development of abdominal segments.

5-day old mxte00436/Df(2L)Exel6010 females produce approximately 80% as many eggs as controls, but the difference becomes more pronounced as the females age (mutant females laying only approximately 25% as many eggs as controls at 20 days old). The germaria of 21-day old mxte00436/Df(2L)Exel6010 females contain fewer germline cells than wild-type controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
CG2950e00436
mxte00436
Name Synonyms
Secondary FlyBase IDs
    References (2)