Amino acid replacement: S350F.
C24165285T
S350F | Apc2-PA; S330F | Apc2-PB; S350F | Apc2-PC
S350F
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
The cuticle of an average Apc2b5 maternal/zygotic embryo shows an anterior hole, is 50-60% the length of wild-type and has 3 patches of denticles remaining. This cuticle phenotype is less severe when embryos are raised at 180C.
Apc2 alleles can be divided into three categories based on their embryonic cuticle phenotypes, from weak to moderate to strong: Apc2e90 = Apc2b5 = Apc2N175K < Apc2c9 = Apc2ΔS = Apc2d40 < Apc2g41 = Apc2f90 = Apc2g10.