FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Eb1B13
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General Information
Symbol
Dmel\Eb1B13
Species
D. melanogaster
Name
FlyBase ID
FBal0239955
Feature type
allele
Associated gene
Dmel\Eb1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    A deletion resulting from the imprecise excision of a local P element.

    (Webb et al., 2009)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Embryos in the offspring of Eb1B13 mothers do not have incomplete actin rings and exhibit partially extended actin pseudocleavage furrows. Approximately 25% of these embryos have actin caps during metaphase. These caps appear to be associated with severe spindle disruption. Spindles display a range of morphological abnormalities. These embryos exhibit disordered "mats" of actin associated with regions of significant nuclear loss.

        (Webb et al., 2009)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        NOT Enhancer of
        Statement
        Reference

        Eb1B13/Eb1[+] is a non-enhancer of cortical actin cytoskeleton | embryonic stage 4 | maternal effect phenotype of Apc2g10

        (Webb et al., 2009)
        NOT Suppressor of
        Statement
        Reference

        Eb1B13/Eb1[+] is a non-suppressor of cortical actin cytoskeleton | maternal effect | embryonic stage 4 phenotype of Apc2g10

        (Webb et al., 2009)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Apical actin in the offspring of Eb1B13/+; Apc2g10 mothers appears normal. Furthermore, there is no significant increase in the percentage of incomplete actin rings in these embryos as compared to wild-type.

        (Webb et al., 2009)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Eb1B13
        (Webb et al., 2009)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)